Prime Fertility Center

ICSI or Intracytoplasmic Sperm Injection is one of the reproductive technologies for infertile couples that has a similar method to the In Vitro Fertilization (IVF), which is egg stimulation and egg retrieval, but fertilizing outside the body by injection a single sperm into the egg directly. Only 1 healthiest sperm is selected then injected into 1 female's egg. After that, the fertilized egg will be cultured in the LAB until the embryo is mature and healthy, then transferring back into the uterine cavity and continue to grow as a baby. This method can help reduce the problems of abnormal fertilization occurred from sperm and egg.

ICSI is suitable for:

- The couple who failed with IUI or IVF method

- The couple who prefers to screen the genetic diseases of the embryo

- Male with low sperm count or severe abnormal sperm

- Sterile couple

- Female who is over 35 years old with low egg count, unqualified egg

Success rate 30% - 40% per cycle

ICSI Procedures:

1. Doctor consultation for health check up

2. Ovarian Stimulation

3. Injection for inducing ovum maturity

4. Egg-Sperm Pick Up

5. ICSI

6. Embryo Culture

7. Transfer embryo to the uterine cavity

8. Pregnancy Test

Treatment List and Services

- Ovarian Stimulation Medication not over 3,000 IU 

- Transvaginal ultrasound during ovarian stimulation not over 4 times

- Doctor visits during ovarian stimulation depend on the doctor's consideration not over 4 visits

- Blood test for hormonal level during ovarian stimulation not over 4 times

- Anti ovulation medicine not over 4 doses

- Inducing ovum maturity injection medicine not over 2 doses

- Ovum Retrieval 1 time

- Anesthesia 1 dose

- Gynaecologist for ovum retrieval procedure 1 visit

- Anesthesiologist for ovum retrieval procedure 1 visit

- Operating & Recovery room  1 time

- Standard medical services, equipment, and supplies 

- Home medicine after ovum retrieval 

- Egg and Sperm preparation 1 time

- HA ICSI 1 time

- Laser assisted hatching 1 time

- Embryo culture 1 time 

-  Embryo Freezing 1 year for 5 embryos 

***Doctor visit and medication depend on the doctor's consideration***

Services NOT INCLUDING

- Male and Female Pre-Stimulation LAB

- Pergoveris Medicine if needed

- Cetrotide or Orgalutran medicine after Ovum retrieval and medication for reducing ascites

- Embryo's Chromosome Testing

- Embryo Transfer

IUI or Intrauterine Insemination is one of the assisted reproductive technologies that helps to solve infertility in the way that is similar to nature. The procedure is to inject some sperm into female's uterus during the ovulation period. This procedure will make it easy for the sperm to approach the fallopian tube then fertilize with the egg naturally

Suitable for :

– Female not over 37 years old.

– Male has normal or slightly abnormal sperm

Success rate : approximately 10-20% per cycle, and 40-50% in four to six cycles.

IUI Procedures 

1. Consult with the doctor, physical check-up, planning for IUI

2. Ovarian stimulation 

3. Ovulation inducing injection

4. IUI

5. Pregnancy test 

Treatment List and Services

- Doctor consultation during ovarian stimulation  (depend on the doctor's appointment)

- Ultrasound during ovarian stimulation (depend on the doctor's consideration)

- Oral medication for ovarian stimulation not over 10 tablets

- Inducing ovum maturity injection medicine 1 dose

- Standard medical services, equipment, and supplies during ovarian stimulation

- Intrauterine Insemination 1 time

- Doctor fee for IUI 1 time

- Operating and Recovery room 1 time

- Standard Medical equipment and supplies for preparation and IUI

Services NOT INCLUDING

- Male and Female Pre-Stimulation LAB before eggs stimulation

- Ovarian stimulation injection medicine (if needed)

- Blood test for pregnancy after IUI 

Egg freezing is a medical technology that extracts women’s eggs out of ovaries to freeze by vitrification technology that can store the eggs for decades. Preventing the eggs from deterioration by aging and being ready to use right away for the future need. 

Suitable for women in these groups:

- Age not over 35 yrs.

- Not ready for pregnancy

- Patients before getting some medical treatments, e.g., radiation or chemotherapy that can harm the fertility

Ovarian stimulation and Ovum retrieval procedure

1. Consult with the doctor, physical check-up, planning for treatment

2. Intermittently inject ovum stimulation medicine for 14 days

3. Inducing ovum maturity injection

4. Retrieve ovum through vagina

Treatment List and Services

- Ovarian Stimulation medication not over 1800 IU  

- Transvaginal ultrasound during ovarian stimulation not over 4 times

- Doctor visits during ovarian stimulation not over 4 visits

- Blood test for hormonal level during ovarian stimulation not over 4 time

- Anti ovulation medicine not over 4 doses

- Inducing ovum maturity injection medicine not over 2 doses

- Ovum retrieval 1 time

- Anesthesia 1 dose

- Gynaecologist for ovum retrieval procedure 1 visit

- Anesthesiologist for ovum retrieval procedure 1 visit

- Operation and Recovery room 1 time

- Standard Medical services, equipment, and supplies

- Home medicine

- Egg Freezing for 1 year not over 18 ovums

****Doctor visit and medication depend on the doctor's consideration***

Services NOT INCLUDING

- Pre-Stimulation LAB before ovarian stimulation

- Pergoveris Medicine if needed

- Cetrotide or Orgalutran medicine after Ovum retrieval and medication for reducing ascites

The objective of Male Pre-Stimulation LAB for IUI or ICSI is to find any diseases or abnormalities that could affact fertility. This test will benefit infertility treatment.

Suggestions

- No need for fasting before the test

- Men should refrain from ejaculating for 2-7 days to ensure the accuracy of the semen quality test results.

Treatment List and Services

- Male Pre Stimulation LAB (blood group, thalassemia, HIV, hepatitis B, C, syphilis) before ovarian stimulation 1 time

- Semen Analysis before ovarian stimulation 1 time

- Doctor consultation 1 visit

- Medical Supplies

- Medical Service

- Nursing and Midwifery Charges

Services NOT INCLUDING

- Additional Blood Tests for finding spouse's abnormalities depend on the doctor's consideration. The expenses is charged depending on the service recipient for each case.

The objective of Female Pre-Stimulation LAB for ICSI or Egg Freezing is to find any diseases or abnormalities that could affact fertility. This test will benefit infertility treatment.

Treatment List and Services

- Female Pre Stimulation LAB (blood group, thalassemia, HIV, hepatitis B, C, syphilis, AMH, FSH, thyroid hormone, estrogen) before ovarian stimulation 1 time

- Transvaginal Ultrasound 1 time

- Doctor consultation 1 visit

- Medical Supplies

- Medical Service

- Nursing and Midwifery Charges

Services NOT INCLUDING

- Additional Blood Tests for finding spouse's abnormalities depend on the doctor's consideration. The expenses is charged depending on the service recipient for each case.

The objective of Female Pre-Stimulation LAB for IUI is to find any diseases or abnormalities that could affact fertility. This test will benefit infertility treatment.

Treatment List and Services

- Female Pre Stimulation LAB (blood group, thalassemia, HIV, hepatitis B, C, syphilis) before ovarian stimulation 1 time

- Transvaginal Ultrasound 1 time

- Doctor consultation 1 visit

- Medical Supplies

- Medical Service

- Nursing and Midwifery Charges

Services NOT INCLUDING

- Additional Blood Tests for finding spouse's abnormalities depend on the doctor's consideration. The expenses is charged depending on the service recipient for each case.

Premarital & Preconception Check Up package consists of 14 tests. This package helps spouses know their fertility, congenital disorder, and genetic disease. It is suitable for couples planning for a baby naturally and couples receiving infertility treartment.

Suggestions

- No need for fasting before the test

- Men should refrain from ejaculating for 2-7 days to ensure the accuracy of the semen quality test results.

Treatment List and Services

- Doctor consultation 1 time

- Semen analysis 1 time

- Pelvic ultrasound 1 time

- Complete blood count test 1 time

- Blood group RH test 1 time

- Blood group ABO test 1 time

- Thalassemia test 1 time

- Anti HIV 1 time

- Anti HCV test 1 time

- HBsAg test 1 time

- Syphilis test 1 time

- Anti HBs test 1 time

- Rubella IgG test 1 time

- Thyroid hormone test 1 time

Services NOT INCLUDING

 Additional Tests for finding spouse's abnormalities depend on the doctor's consideration. For an example, a spouse with congenital disorder or genetic disease.

Hysteroscopy is an examination procedure to identify some disorders inside the uterine cavity by putting a tiny camera through the cervix. It can help the doctor to evaluate some pelvic health issues efficiently while the diagnosis cannot be performed by a general medical checkup e.g., PV test, Ultrasound, etc. This procedure is getting more popularity in gynecological diagnosis and treatment as it is taking less time, giving more accuracy and better result after treatment.

Benefits of Hysteroscopy

* This procedure effectively increases pregnancy rate and helps make embryo implantation easier because hysteroscopy will allow us to see problems such as,  Polyp, Adhesion, and Endometritis. Make it easier to fix those problems before embryo transfer during ICSI or during natural method.

Suitable for:

* Couples who have failed from natural method.

* Couples who have failed from IUI (Intra-Uterine Insemination) program.

* Couples who have failed from ICSI program despite good grade and quality embryo and positive feedback from chromosome testing.

Treatment List and Services

- Blood Test 1 time

- Doctor fee 1 time

- Transvaginal ultrasound 1 time

- Anesthesia 1 dose

- Anesthesiologist fee 1 time

- Surgical fee 1 time

- Operating and Recovery Room 1 time

- Standard medical survices, equipment, and supplies

- Home medicine

Services NOT INCLUDING

- Biopy (in case of polyps) and Pathologic tissue study

Hysteroscopy is an examination procedure to identify some disorders inside the uterine cavity by putting a tiny camera through the cervix. It can help the doctor to evaluate some pelvic health issues efficiently while the diagnosis cannot be performed by a general medical checkup e.g., PV test, Ultrasound, etc. This procedure is getting more popularity in gynecological diagnosis and treatment as it is taking less time, giving more accuracy and better result after treatment.

Benefits of Hysteroscopy

* This procedure effectively increases pregnancy rate and helps make embryo implantation easier because hysteroscopy will allow us to see problems such as,  Polyp, Adhesion, and Endometritis. Make it easier to fix those problems before embryo transfer during ICSI or during natural method.

Suitable for:

* Couples who have failed from natural method.

* Couples who have failed from IUI (Intra-Uterine Insemination) program.

* Couples who have failed from ICSI program despite good grade and quality embryo and positive feedback from chromosome testing.

Treatment List and Services

- Surgical fee 1 time

- Operating and Recovery Room 1 time

- Standard medical equipment and supplies

- Home medicine

Services NOT INCLUDING

- Biopy (in case of polyps) and Pathologic tissue study

Prime Fertility Clinic's Semen Analysis is the process of evaluation to determine the quality of sperm, measured by sperm count, pH, concentration, survival rate, motility, morphology, and white blood cell count. If any abnormalities such as, yeast, mold, bacteria are found by using microscope, the clinic will inform the result later on. For those who are interested in proceeding semen analysis, appointments can be made 1 day in advance. There is no need for fasting before the test. However, men should refrain from ejaculating for 2-7 days to ensure the accuracy of the semen quality test results. The clinic will inform the result within 1.5 hours.

Treatment List and Services

- Semen Analysis 1 time

- Doctor Fee 1 visit

- Medical Service and Supplies

Suggestions

- No need for fasting before the test

- Men should refrain from ejaculating for 2-7 days to ensure the accuracy of the semen quality test results.

Services NOT INCLUDING

- Expenses for blood test depends on doctor's consideration (To find the abnormalities of the petients). The expenses is charged depending on the service recipient for each case.

PESA / TESA / TESE is the solution for severe cases of male infertility such as an ejaculation, the absence of sperm on a semen analysis may be due to azoospermia, cause from congenital bilateral absence of the vas deferens, vasectomy or no viable sperm after ejaculation, death of all sperm ejaculated or testicular inflammation due to the mumps virus or other causes.

* Percutaneous Epididymal Sperm Aspiration (PESA): This involves the same needle and syringe technique but the needle is placed directly into the epididymis.

* Testicular Sperm Aspiration (TESA): This involves placing a needle attached to a syringe through the skin of the scrotum and simply sucking out the fluid inside the testicle

* Testicular Sperm Extraction (TESE): This is an open surgical biopsy technique to remove a few testicular tissues and extract to find the sperm.

Treatment List and Services

- Blood Test 1 time

- Surgical Fee 1 visit 

- Anesthesiologist Fee  1 visit

- Anesthesia 1 dose

- Operating Cost & Recovery Room 1 time

- Standard Medical Service, Supplies and Equipment 

- Home Medicine 

*** Medication applied depends on doctor's consideration***

Services NOT INCLUDING

- Sperm freezing for the next ICSI process in case of good sperm quality

MACS Sperm (Magnetic-Activated Sorting)

MACS is a technique used to select qualified spermatozoa by removing apoptotic spermatozoa which will die without achieving fertilization, and selects the healthy ones with good motility, viability, and morphology, thus increasing the possibility of pregnancy.

The MACS technique consists of the use of tiny biodegradablemagnetic particles that have an antibody attached (the protein annexin V) which is able to detect apoptotic spermatozoa. Meanwhile, the healthy spermatozoa are able to draw through the column. 

This way, we can obtain healthy spermatozoa with the best physiological qualities for use in assisted reproductive treatments.

Treatment List and Services

- Sperm collection 1 time

- Doctor Fee 1 time

- MACS Sperm 1 time

- LAB cost

- Standard Medical Service, Supplies and Equipment

P.RP (P.latelet Rich P.lasma) is a process in that platelets are spun until the concentration is 3-5 times higher than the normal blood and then injected into an organ or tissue to stimulate the cell development. Platelets have many properties. For example, Cytokines, Hormones and various Growth Factors.

P.RP procedures begin with blood drawing and placing in a centrifuge to concentrate the platelets. These platelets are injected directly to the patient’s own ovary.

There are some studies about P.RP in fertility treatment. Over the past several years, patients who have diminished ovarian reserve, ovarian failure, as well as women who reach or nearly approach the menopause prefer to stimulate their eggs rather than using the egg donation. After receiving P.RP treatment, we found positive outcomes in some cases. The better feedback and more eggs obtained may lead pregnancy and delivery successfully. 

Treatment List and Services

- Blood test 1 time

- Doctor fee not over 3 visits 

- Transvaginal ultrasound 1 time 

- Anesthesia 1 dose 

- Anesthesiologist fee 1 visit 

- Standard medical equipment and supplies 

- Surgical fee 1 time

- Operating & Recovery Room 1 time

- P.RP (P.latelet Rich P.lasma) preparation 1 time

- P.RP (P.latelet Rich P.lasma) intraovarian infusion 1 time

Services NOT INCLUDING

- AMH test after P.RP treatment

- Home medicine

P.RP (P.latelet Rich P.lasma) is a process in that platelets are spun until the concentration is 3-5 times higher than the normal blood and then injected into an organ or tissue to stimulate the cell development. Platelets have many properties. For example, Cytokines, Hormones and various Growth Factors.

P.RP procedures begin with blood drawing and placing in a centrifuge to concentrate the platelets. These platelets are injected directly to the patient’s own uterine cavity.

There are some studies about P.RP in fertility treatment. Over the past several years, patients who have thin endometrium get positive outcomes in some cases after receiving P.RP treatment. Then lead the successful embryo transfer and pregnancy.

Treatment List and Services

- Doctor fee 1 visit 

- Transvaginal ultrasound 1 time

- Standard medical equipment and supplies

- Surgical fee 1 time

- Operating and Recovery Room 1 time 

- P.RP (P.latelet Rich P.lasma) preparation 1 time

- P.RP (P.latelet Rich P.lasma) intrauterine infusion 1 time

Services NOT INCLUDING

- Expenses before P.RP program which are doctor fee, ultrasound, blood test according to the doctor's consideration 

Pelvic Ultrasound is a type of gynecological examination by transvaginal ultrasound to check the abnormalities of uterus and ovaries. The test can detect some conditions that may cause infertility such as ovarian cysts, ovarian tumors, myoma uteri, endometrial polyps. 

Suitable for:

- Woman who had sexual contact should get the test annually 

- Woman with irregular period or abnormal period pain

- Woman with family planning

Treatment List and Services

- Pelvic Ultrasound 1 time

- Medical Supplies

Services NOT INCLUDING

- Doctor Fee 

- Medical Service

- Nursing and Midwifery Charges

Preimplantation Genetic Testing: PGT refers to a technique for detecting the abnomorlities across all 22 autosomes and the X and Y chromosomes of embryo during pre-implantation, increasing the pregnancy rate.

Benefits:

* Detect the abnomalities of the embryo during preimplantation

* Reduce chance of abortion caused by abnomalities of the embryo

* Able to choose the best embryo

* Increase more 60-80 % of pregnancy rate

* Reduce chance of genetic disorders

* 99% Accuracy

* Shorten the wait for pregnancy 

Suitable for:

1. Patients having treatment when the female age is over 35 (Advanced Maternal Age: AMA).

2. Patients that have had IVF failure.

3. Patients knowing that themselves or any of their family members has any genetic disease and chromosomal translocations.

4. Patients that have had recurrent miscarriages.

Next Generation Sequencing (NGS) NGS is the special technique in detecting abnormalities of a gene deep to its base sequences, the smallest component of one chromosome, by comparing these sequences of abnormal gene to the normal one. Therefore, this technique can be highly accurate in detecting the abnormalities occurring in any genes, and is now applied to pre-implantation genetic screening (PGS), one of the best means for diagnosis in the present.

Treatment List and Services

- Preimplantation Genetic Testing (PGT-A (NGS)) for the first 2 embryos

- 1-year freezing for the first 2 embryos

- Biopsy for the first 2 embryos

Frozen Embryo Transfer (Frozen Cycle) is the process of embryo transplantation into the prepared endometrium after thawing frozen embryo.

Benefits of FET:

* The success rate is 32% higher than Fresh Embryo Transfer. Abortion rate tends to decrease as Frozen Embryo Transfer has more time for endometrium preparation. While the Fresh cycle, the endometrium will be stimulated to retrieve ovums, causing endometrial hyperplasia which does not support the implantation.

* The process can be used for couples who need Preimplantation Genetic Testing. As before the genetic testing procedure, the placenta cells biopsy is needed. Therefore, freezing embryo is needed before the genetic testing procedure.

Treatment List and Services

- Frozen embryo transfer 1 time

- Gynaecologist for embryo transfer 1 time

- Operating Cost, LAB Cost and Recovery Room 1 time

- Embryo thawing 1 time

- Luteal phase medicine 15 days  

Services NOT INCLUDING

- Blood test before embryo transfer (in case the previous test is over 3 months)

- Expenses during endometrial preparation consist of Doctor Fee + Ultrasound + Medication + LAB test 

- Embryo implantation support medicine

- Blood test for pregnancy after embryo transfer 

Human Papillomavirus 9-valent vaccine for an adult aged 15 yrs. or over helps to prevent cervical, vaginal, anal cancer or genital warts caused by certain types of HPV (types 6, 11, 16, 18, 31, 33, 45, 52 and 58).

- 1st dose on your first visit

- 2nd dose in 1-2 months later

- 3rd dose in 6th month from 1st dose

Cautions:

- A person who has been married or had sexual contact should receive the pelvic ultrasound to screen the cervical cancer or human papillomavirus before getting this vaccine.

- This vaccine is not allowed for a person with serious yeast allergy or the vaccine allergy.

Treatment List and Services

- GARDASIL 9 for Adult (Human Papillomavirus 9-valent Vaccine, Recombinant), 3 Doses

- Medical Supplies

Services NOT INCLUDING

- Doctor Fee 

- Medical Service

- Nursing and Midwifery Charges

Human Papillomavirus 9-valent vaccine for a child aged 9-14 yrs. helps to prevent cervical, vaginal, anal cancer or genital warts caused by certain types of HPV (types 6, 11, 16, 18, 31, 33, 45, 52 and 58).

- 1st dose on your first visit

- 2nd dose in 6th month from 1st dose

Cautions:

- This vaccine is not allowed for a person with serious yeast allergy or the vaccine allergy.

Treatment List and Services

- GARDASIL 9 for Child (Human Papillomavirus 9-valent Vaccine, Recombinant) 2 Doses

- Medical Supplies

Services NOT INCLUDING

- Doctor Fee 

- Medical Service

- Nursing and Midwifery Charges

ThinPrep Pap Test is a standard examination to screen a cervical cancer. The cervical cells will be collected by liquid-based cytology (LBC). This method helps to collect more sample cells, clearer cells and evaluate the early-stage cancer cells better than the old method which is Pap Smear test.  

Suitable for:

- Woman who had sexual contact

- Woman at 30 yrs. or over

When to get tested: Every 2 years

***Can extend to be every 5 years in case the ThinPrep Pap Test is proceeded together with HPV DNA testing.

Treatment List and Services

- ThinPrep Pap Test 1 time

- Medical Supplies

Services NOT INCLUDING

- Doctor Fee 

- Medical Service

- Nursing and Midwifery Charges

Hepatitis B (HBV) vaccine (3 doses) for adults, aged more than 10 years:

- 1st dose on your first visit

- 2nd dose in 1-2 months later

- 3rd dose in 6th month from 1st dose

Recommended for:

- Anyone who never received this vaccine

- Those who are receiving blood transfusion

- People at high risk for infection due to lifestyle, job, country of living, etc.

Caution:

This vaccine is not suitable for a person with yeast allergy or has not recovered from acute illness.

Treatment List and Services

- HBV Vaccine 3 Doses

- Medical Supplies

Services NOT INCLUDING

- Doctor Fee 

- Medical Service

- Nursing and Midwifery Charges

VaxigripTetra, Influenza Vaccine 4 Strains for 2024

 Vaccine intended for use against 4 strains of influenza virus as recommended by the World Health Organization (WHO).

 Suitable for:

 * Children aged 6 months and over

 * People over 65 years of age

 * Pregnant women or women after childbirth (within 2 weeks)

 * People with congenital disease succh as, diabetes, heart disease, respiratory disease, HIV

 Cautions:

 • No vaccination for people with severe egg protein allergy

 • Vaccination should be postponed if there is a fever or acute illness

Treatment List and Services

- Influenza Vaccine 4 Strains1 dose

 - Medical Supplies

Services NOT INCLUDING

- Doctor Fee (in case of doctor visit)

- Medical Service

- Nursing and Midwifery Charges

Vaccine Against Dengue: Qdenga, Dengue Tetravalent Vaccine (Live, Attenuated)

 Benefits: New vaccine from Germany, safe, be the first vaccine that available for those who used to have or never have dengue hemorrhagic fever. There is no need of immunity testing before vaccination.

 Efficacy: The vaccine can prevent dengue viral infection for 80%. It covers all 4 strains of dengue virus which are DENV-1, DENV-2, DENV-3, and DENV-4. Moreover, it can lower the risks of hospitalization for 90%.

 Suitable for: Individual at age 4-60 years

 Dosage and vaccination schedule: 2 Doses by subcutaneous injection. First dose is upon your convenient time. Second dose will be proceeded in the third month after the first dose. However, people who used to have dengue hemorrhagic fever can receive this vaccine when getting recovery from the disease for 6 months.

 Side effects: People may experience the pain on the injection area, headache, muscle pain but the symptoms will be gone spontaneously within 1-3 days.

 Cautions: Since it is a live vaccine, it is not recommended to those who are taking immunosuppressants, patients during chemotherapy, HIV patients, people with immune disorders, pregnant women, and breastfeeding women.

*Treatment List and Services

- Dengue vaccine 2 doses

- Medical Supplies

*Services NOT INCLUDING

- Doctor Fee 

- Medical Service

-Nursing and Midwifery Charges

The vaccine helps protect against the 13 types of pneumococcal bacteria. Adults 18 years old or over receive 1 shot on their selected visit. 

Recommended for:

- Adults18 yrs. or over and elderly 65 yrs. or over

- Smoking people or people with chronic health conditions, e.g., kidney disease, heart disease, chronic obstructive pulmonary disease, chronic asthma, diabetes

- People with immunodeficiency such as HIV, lymphoma, leukemia

Treatment List and Services

- Pneumococcal Vaccine (Prevnar13) 1 dose

- Medical Supplies

Services NOT INCLUDING

- Doctor Fee 

- Medical Service

- Nursing and Midwifery Charges