Nesther Clinic

It changes facial skin to be brighter and freckleless. With intense antioxidants, it whitens dark melanins with

- Glutathione helps to create pheomelanin (pink-white pigment)

- Vitamin C help stimulate collagen and elastin production and protects the skin from the harmful effects of UV light

- Helps the skin to be fair and bright

- Smoothen skin and tighten pores

- Fades deep freckles away

- Removes dark spots

It is a Beard hair removal by using Diode laser. Diode Laser technology is recommended for hair removal with permanent results, while IPL is recommended for hair reduction. This is because lasers create more heat and light energy directly concentrated to the hair follicle and only target melanin (the pigment that gives hair its colour), while the light energy of IPL diffuses on the skin surrounding the hair follicle.
Treatment takes approximately 15-30 minutes, depending on the area

A thread lift is a cosmetic procedure that aims to lift and sculpt the shape of your face or breasts. It is a non-surgical procedure designed to combat the signs of ageing in the face and neck areas by lifting and tightening the skin, making it look younger, smoother and healthier.

Fat Bomb is a technique for pushing vitamins into the fat layer for the benefit of slimming down to get the desired shape It is a method to reduce fat and reduce cellulite locally. without using a surgical method By bringing 100% natural extracts to help break down excess fat, burn fat and swelling around the cheeks, wattle, cheekbones and also help to lift the body. Not sagging, the drug is concentrated, the face frame looks clearer has more dimensions, and does not destroy collagen at the injection site Helps to tighten pores. And the results work in 3-7 days, do not contain other forms of phosphatidylcholine, caffeine, and L-carnitine because the extract is 100% natural.

Filler Belotero is featured in high flexibility and contains an anesthetic. The filler can last for 18 months. It can solve problems in areas with deep folds caused by the aging process or the increasing age such as nasolabial folds and sunken cheeks

Intense Vitamin C drip with Vitamin B1&B2 is to enhance antioxidants, slow down aging and prevent wrinkles. This vitamin injection nourishes the skin and makes clearer skin together with increse the immune system to strengthen the body to reduce allergy, prevent common cold and other viral disease.

Cytocare is a skin injection product characterized by a clear solution. Nucleic acids Antioxidants, vitamins, minerals, and more than 50 types of minerals that make up rejuvenating complex CT50 contain a variety of substances that feed the skin and antioxidants, which contribute to reducing wrinkles. Restores skin to look more moisturized and radiant.

Aestox is one of the Korean บท็อกซ์ certified by the Thai FDA. Since it contains high purity, Aestox reduces the บท็อกซ์ resistance chance; it gives the fast results of wrinkle removals and faces slimming.

The IV Drip Vitamin Super Slim is designed to boost your metabolism and aid in weight loss. This powerful vitamin infusion enhances your body's ability to burn fat more efficiently, helping you achieve your weight management goals. Perfect for those looking to jumpstart their weight loss journey with a safe and effective treatment.

Restylane filler, one of the certified filler brands, is often used to re-shape the entire face and rejuvenate the skin to maintain a youthful appearance. The brand is good at lifting the skin.

Nabota is a Korean บท็อกซ์ established by DAEWOONGcompany. It is the only Korean บท็อกซ์ brand approved by the U.S. FDA. The highlight of Nabota is that the result comes out very fast, which is suitable for those who want instant results. It is often used to get rid of wrinkles such as furrow, Crow's feet, and glabella. It helps jaw reduction, skin tightening, and facial reshaping to get a slim face.

Ultraformer is about lifting the face, tightening the skin, adjusting the shape of the face, and dissolving fat. You will see results in the first time. It hurts a little but can restore youthfulness to the skin. Using high frequency sound waves Highly concentrated, it releases energy specifically to the desired depth location. Without this surgery or surgery It's called Hifu (blue check mark) machine technology. Brand Ultraformer III is the best Hifu machine, equivalent to ULTHERA because it is a Macrofocus system that has been certified to European standards. Macrofocus

Can last up to 6 months - 1 year, depending on the care of the person receiving the service.

Diode Laser technology is recommended for hair removal with permanent results, while IPL is recommended for hair reduction. This is because lasers create more heat and light energy directly concentrated to the hair follicle and only target melanin (the pigment that gives hair its colour), while the light energy of IPL diffuses on the skin surrounding the hair follicle.

Treatment takes approximately 15-30 minutes, depending on the area

Ultraformer is about lifting the face, tightening the skin, adjusting the shape of the face, and dissolving fat. You will see results in the first time. It hurts a little but can restore youthfulness to the skin. Using high frequency sound waves Highly concentrated, it releases energy specifically to the desired depth location. Without this surgery or surgery It's called Hifu (blue check mark) machine technology. Brand Ultraformer III is the best Hifu machine, equivalent to ULTHERA because it is a Macrofocus system that has been certified to European standards. Macrofocus

Can last up to 6 months - 1 year, depending on the care of the person receiving the service.

Diode Laser technology is recommended for hair removal with permanent results, while IPL is recommended for hair reduction. This is because lasers create more heat and light energy directly concentrated to the hair follicle and only target melanin (the pigment that gives hair its colour), while the light energy of IPL diffuses on the skin surrounding the hair follicle.

Treatment takes approximately 15-30 minutes, depending on the area

Diamond Fat is a premium Korean Meso Fat, certified by FDA (Food and Drug Administration), KFDA, GMP and Thai FDA. Natural plant extracts that help break down fat under the skin. Ready to lift and tighten the face to be slender. The facial frame is clear, the wound looks dimensional. Reduces the size of the cheeks, wattle, upper arms, thighs and abdomen. Strengthen muscles, firmer skin

Ultraformer is about lifting the face, tightening the skin, adjusting the shape of the face, and dissolving fat. You will see results in the first time. It hurts a little but can restore youthfulness to the skin. Using high frequency sound waves Highly concentrated, it releases energy specifically to the desired depth location. Without this surgery or surgery It's called Hifu (blue check mark) machine technology. Brand Ultraformer III is the best Hifu machine, equivalent to ULTHERA because it is a Macrofocus system that has been certified to European standards. Macrofocus

Can last up to 6 months - 1 year, depending on the care of the person receiving the service.

Diode Laser technology is recommended for hair removal with permanent results, while IPL is recommended for hair reduction. This is because lasers create more heat and light energy directly concentrated to the hair follicle and only target melanin (the pigment that gives hair its colour), while the light energy of IPL diffuses on the skin surrounding the hair follicle.

Treatment takes approximately 15-30 minutes, depending on the area

Nabota is a Korean บท็อกซ์ established by DAEWOONGcompany. It is the only Korean บท็อกซ์ brand approved by the U.S. FDA. The highlight of Nabota is that the result comes out very fast, which is suitable for those who want instant results. It is often used to get rid of wrinkles such as furrow, Crow's feet, and glabella. It helps jaw reduction, skin tightening, and facial reshaping to get a slim face.

Made Collagen is an Italian brand used to make mesotherapy. It will be injected with a special technique to stimulate collagen production at 16 points to add moisture to the skin to get a bright face. Moreover, it can reduce acne and allergies while add nutrients, and detox the skin.

Made Collagen activating through 4 steps

1. Detoxification 

2. Metabolism 

3. Nutrients and Cell therapy 

4. Restructuring 

Diode Laser technology is recommended for hair removal with permanent results, while IPL is recommended for hair reduction. This is because lasers create more heat and light energy directly concentrated to the hair follicle and only target melanin (the pigment that gives hair its colour), while the light energy of IPL diffuses on the skin surrounding the hair follicle.

Treatment takes approximately 15-30 minutes, depending on the area

Made Collagen is an Italian brand used to make mesotherapy. It will be injected with a special technique to stimulate collagen production at 16 points to add moisture to the skin to get a bright face. Moreover, it can reduce acne and allergies while add nutrients, and detox the skin.

Made Collagen activating through 4 steps

1. Detoxification 

2. Metabolism 

3. Nutrients and Cell therapy 

4. Restructuring 

"Gouri is a high molecular weight PCL (Polycaprolactone) compound. It is a substance that has been used in melting silk for more than 10 years in the medical field. Its special feature is that it is the first liquid to inject skin rejuvenation. and stimulate collagen can be spread naturally over the face Helps create collagen synthesis that decreases due to aging of the skin that starts to deteriorate.
- Stimulate the creation of new collagen instead of the original that has been lost over time.
- Make the skin look younger again
- Helps lift and tighten the skin to be tighter.
- Restore deep wrinkles to look faded.
- Safe, does not damage the skin tissue"    

Restylane Kysse fillers are the only fillers. Specially designed to inject and correct lip problems The specialty of Restylane Kysse is that it is a fine filler. but stable It can help create a clearer lip line. add moisture fullness and adjust the color of the lips to look brighter

Eye bag surgery is a cosmetic procedure that solves the problem of drooping or visibly raised bags under the eyes through the removal of tissue or part of the fat bags under the eyes.

Give the nostrils a new shape. Reduce the nasal tip. Reduce the bridge. Enhance the balance and harmony between other facial features. Rhinoplasty is a surgery to change the shape of the nose. Because both breathing and the nose's shape are interrelated, a rhinoplasty may sometimes be performed not only to change the way the nose looks but also to improve breathing through the nose

Neuramis filler is good quality and affordable filler. It delivers instant result after the first injection due to the high-quality hyaluronic acid. Because it provides a hard texture and no anesthetic, Neuramis is suitable for filling facial deep folds such as the wrinkles on the cheeks, temples, and chin.

Diode Laser technology is recommended for hair removal with permanent results, while IPL is recommended for hair reduction. This is because lasers create more heat and light energy directly concentrated to the hair follicle and only target melanin (the pigment that gives hair its colour), while the light energy of IPL diffuses on the skin surrounding the hair follicle.

Treatment takes approximately 15-30 minutes, depending on the area

Ultraformer is about lifting the face, tightening the skin, adjusting the shape of the face, and dissolving fat. You will see results in the first time. It hurts a little but can restore youthfulness to the skin. Using high frequency sound waves Highly concentrated, it releases energy specifically to the desired depth location. Without this surgery or surgery It's called Hifu (blue check mark) machine technology. Brand Ultraformer III is the best Hifu machine, equivalent to ULTHERA because it is a Macrofocus system that has been certified to European standards. Macrofocus

Can last up to 6 months - 1 year, depending on the care of the person receiving the service.

Sculptra is a collagen stimulating injection that has been talked about in the skin booster industry for its effectiveness. The highlight that has been talked about is that it can stimulate collagen. Helps restore youthfulness to the skin. Maintain results for up to 25 months or approximately 2 years and is the first Collagen Stimulator in the world and the only one certified by the US FDA, ensuring safety.

This FDA-approved laser treatment is designed for the precise removal of one mole or skin tag per session. The advanced laser technology effectively targets and eliminates unwanted skin imperfections, providing a safe and efficient solution.

It is a Mustache hair removal by using Diode laser. Diode Laser technology is recommended for hair removal with permanent results, while IPL is recommended for hair reduction. This is because lasers create more heat and light energy directly concentrated to the hair follicle and only target melanin (the pigment that gives hair its colour), while the light energy of IPL diffuses on the skin surrounding the hair follicle. Treatment takes approximately 15-30 minutes, depending on the area

Restylane Kysse fillers are the only fillers. Specially designed to inject and correct lip problems The specialty of Restylane Kysse is that it is a fine filler. but stable It can help create a clearer lip line. add moisture fullness and adjust the color of the lips to look brighter

Filler Belotero is featured in high flexibility and contains an anesthetic. The filler can last for 18 months. It can solve problems in areas with deep folds caused by the aging process or the increasing age such as nasolabial folds and sunken cheeks

Made Collagen is an Italian brand used to make mesotherapy. It will be injected with a special technique to stimulate collagen production at 16 points to add moisture to the skin to get a bright face. Moreover, it can reduce acne and allergies while add nutrients, and detox the skin.

Made Collagen activating through 4 steps

1. Detoxification 

2. Metabolism 

3. Nutrients and Cell therapy 

4. Restructuring 

A thread lift is a cosmetic procedure that aims to lift and sculpt the shape of your face or breasts. It is a non-surgical procedure designed to combat the signs of ageing in the face and neck areas by lifting and tightening the skin, making it look younger, smoother and healthier.

Increases the level of NAD+ in the body to accelerate the action of aging cells. Converted into energy to help restore the nervous system and brain cell function. and rejuvenate the body To be fresh and radiant, affecting the skin and shape, which NAD+ IV Therapy will help reverse aging. Rejuvenate the whole system of body health and skin. Including helping to speed up the metabolism in the body Both youthfulness, good shape and sustainable health.

Nabota is a Korean บท็อกซ์ established by DAEWOONGcompany. It is the only Korean บท็อกซ์ brand approved by the U.S. FDA. The highlight of Nabota is that the result comes out very fast, which is suitable for those who want instant results. It is often used to get rid of wrinkles such as furrow, Crow's feet, and glabella. It helps jaw reduction, skin tightening, and facial reshaping to get a slim face.

Increases the level of NAD+ in the body to accelerate the action of aging cells. Converted into energy to help restore the nervous system and brain cell function. and rejuvenate the body To be fresh and radiant, affecting the skin and shape, which NAD+ IV Therapy will help reverse aging. Rejuvenate the whole system of body health and skin. Including helping to speed up the metabolism in the body Both youthfulness, good shape and sustainable health.

Aestox is one of the Korean บท็อกซ์ certified by the Thai FDA. Since it contains high purity, Aestox reduces the บท็อกซ์ resistance chance; it gives the fast results of wrinkle removals and faces slimming.

A thread lift is a cosmetic procedure that aims to lift and sculpt the shape of your face or breasts. It is a non-surgical procedure designed to combat the signs of ageing in the face and neck areas by lifting and tightening the skin, making it look younger, smoother and healthier.

Acne Treatment: It is a treatment for reducing clogged acne, inflamed acne, allergic rashes, and reducing various irritations. Including helping to nourish the skin. It makes the skin soft, moisturized and noticeably healthier. It can be considered an effective treatment. because it not only helps to cure acne only But it also helps prevent new acne. And help adjust the skin to return to normal quickly after having acne for a long time.

It is an underarm hair removal by using Diode laser. Diode Laser technology is recommended for hair removal with permanent results, while IPL is recommended for hair reduction. This is because lasers create more heat and light energy directly concentrated to the hair follicle and only target melanin (the pigment that gives hair its colour), while the light energy of IPL diffuses on the skin surrounding the hair follicle.
Treatment takes approximately 15-30 minutes, depending on the area

Aestox is one of the Korean บท็อกซ์ certified by the Thai FDA. Since it contains high purity, Aestox reduces the บท็อกซ์ resistance chance; it gives the fast results of wrinkle removals and faces slimming.

Made Collagen is an Italian brand used to make mesotherapy. It will be injected with a special technique to stimulate collagen production at 16 points to add moisture to the skin to get a bright face. Moreover, it can reduce acne and allergies while add nutrients, and detox the skin.
Made Collagen activating through 4 steps
1. Detoxification
2. Metabolism
3. Nutrients and Cell therapy
4. Restructuring

Mesofat Phytobella brandis a product from Korea. The drug contains natural extracts; therefore, it is safe. It can be injected to dissolve fat in many parts of the body such as neck wattles under the chin, cheeks, upper arms, thighs, hips and calves, helping to tighten the skin and treat edema. (6 CC/time)

Aestox is one of the Korean บท็อกซ์ certified by the Thai FDA. Since it contains high purity, Aestox reduces the บท็อกซ์ resistance chance; it gives the fast results of wrinkle removals and faces slimming.

Restylane filler, one of the certified filler brands, is often used to re-shape the entire face and rejuvenate the skin to maintain a youthful appearance. The brand is good at lifting the skin.

FUE hair transplants involves taking individual hair follicles and transplanting them to thinning or balding areas of the scalp.

Diode Laser technology is recommended for hair removal with permanent results, while IPL is recommended for hair reduction. This is because lasers create more heat and light energy directly concentrated to the hair follicle and only target melanin (the pigment that gives hair its colour), while the light energy of IPL diffuses on the skin surrounding the hair follicle.

Treatment takes approximately 15-30 minutes, depending on the area

Meso Fat BABI Neo One brandis a product from Korea. It is suitable for people with sagging cheek problems. The product is able to break down fat and tighten the face. The result will show within 3 days. It is often used to inject to reduce the double chin.

Nabota is a Korean บท็อกซ์ established by DAEWOONGcompany. It is the only Korean บท็อกซ์ brand approved by the U.S. FDA. The highlight of Nabota is that the result comes out very fast, which is suitable for those who want instant results. It is often used to get rid of wrinkles such as furrow, Crow's feet, and glabella. It helps jaw reduction, skin tightening, and facial reshaping to get a slim face.

Diode Laser technology is recommended for hair removal with permanent results, while IPL is recommended for hair reduction. This is because lasers create more heat and light energy directly concentrated to the hair follicle and only target melanin (the pigment that gives hair its colour), while the light energy of IPL diffuses on the skin surrounding the hair follicle.

Treatment takes approximately 15-30 minutes, depending on the area

xeo.min (botulinum To.xin, Germany) is a development of Allergan and Dysport, emphasizing purity.According to research, it is a brand that doesn't case the drug resistant. Doctors will use it on patients who have been resistant to the drug before, but must be spaced 3-4 years before injecting into patients

Diode Laser technology is recommended for hair removal with permanent results, while IPL is recommended for hair reduction. This is because lasers create more heat and light energy directly concentrated to the hair follicle and only target melanin (the pigment that gives hair its colour), while the light energy of IPL diffuses on the skin surrounding the hair follicle.

Treatment takes approximately 15-30 minutes, depending on the area

It is a whole pubic hair removal by using Diode laser. Diode Laser technology is recommended for hair removal with permanent results, while IPL is recommended for hair reduction. This is because lasers create more heat and light energy directly concentrated to the hair follicle and only target melanin (the pigment that gives hair its colour), while the light energy of IPL diffuses on the skin surrounding the hair follicle.
Treatment takes approximately 15-30 minutes, depending on the area

Radiesse is a type of dermal filler composed primarily of Calcium Hydroxylapatite (CaHA), which belongs to the group of collagen-stimulating biostimulators. Its unique advantage lies in its ability to stimulate both collagen and elastin production. This dual action provides immediate volumizing results while also gradually reducing the appearance of deep wrinkles in the long term. It is particularly suitable for addressing deep facial wrinkles and folds, such as nasolabial folds and marionette lines, as well as for hand rejuvenation.    

It is a high vitamin C intake into the bloodstrem together with vitamin B and many other minerals to help increase antioxidants and essential minerals that the body needs. It is a method that alternative medicine is used to treat many diseases such as asthma, migrane, fatigue or muscle aches.

Diode Laser technology is recommended for hair removal with permanent results, while IPL is recommended for hair reduction. This is because lasers create more heat and light energy directly concentrated to the hair follicle and only target melanin (the pigment that gives hair its colour), while the light energy of IPL diffuses on the skin surrounding the hair follicle.

Treatment takes approximately 15-30 minutes, depending on the area

Diode Laser technology is recommended for hair removal with permanent results, while IPL is recommended for hair reduction. This is because lasers create more heat and light energy directly concentrated to the hair follicle and only target melanin (the pigment that gives hair its colour), while the light energy of IPL diffuses on the skin surrounding the hair follicle.

Treatment takes approximately 15-30 minutes, depending on the area

Filler Belotero is featured in high flexibility and contains an anesthetic. The filler can last for 18 months. It can solve problems in areas with deep folds caused by the aging process or the increasing age such as nasolabial folds and sunken cheeks

The IV Drip Vitamin Perfect White Detox is specially formulated to rejuvenate tired and dull skin, particularly for those with little rest. This vitamin infusion detoxifies the body while brightening and revitalizing the skin, leaving you with a refreshed and radiant complexion.

Made Collagen is an Italian brand used to make mesotherapy. It will be injected with a special technique to stimulate collagen production at 16 points to add moisture to the skin to get a bright face. Moreover, it can reduce acne and allergies while add nutrients, and detox the skin.
Made Collagen activating through 4 steps
1. Detoxification
2. Metabolism
3. Nutrients and Cell therapy
4. Restructuring

Advanced laser treatment for hair removal, designed to rejuvenate your facial skin. This state-of-the-art technology effectively removes unwanted hair while promoting clearer and more youthful-looking skin.

Restylane Kysse fillers are the only fillers. Specially designed to inject and correct lip problems The specialty of Restylane Kysse is that it is a fine filler. but stable It can help create a clearer lip line. add moisture fullness and adjust the color of the lips to look brighter

Ultraformer is about lifting the face, tightening the skin, adjusting the shape of the face, and dissolving fat. You will see results in the first time. It hurts a little but can restore youthfulness to the skin. Using high frequency sound waves Highly concentrated, it releases energy specifically to the desired depth location. Without this surgery or surgery It's called Hifu (blue check mark) machine technology. Brand Ultraformer III is the best Hifu machine, equivalent to ULTHERA because it is a Macrofocus system that has been certified to European standards. Macrofocus

Can last up to 6 months - 1 year, depending on the care of the person receiving the service.

Restylane Kysse fillers are the only fillers. Specially designed to inject and correct lip problems The specialty of Restylane Kysse is that it is a fine filler. but stable It can help create a clearer lip line. add moisture fullness and adjust the color of the lips to look brighter

Restylane filler, one of the certified filler brands, is often used to re-shape the entire face and rejuvenate the skin to maintain a youthful appearance. The brand is good at lifting the skin.

Sculptra is a collagen stimulating injection that has been talked about in the skin booster industry for its effectiveness. The highlight that has been talked about is that it can stimulate collagen. Helps restore youthfulness to the skin. Maintain results for up to 25 months or approximately 2 years and is the first Collagen Stimulator in the world and the only one certified by the US FDA, ensuring safety.

Aestox is one of the Korean บท็อกซ์ certified by the Thai FDA. Since it contains high purity, Aestox reduces the บท็อกซ์ resistance chance; it gives the fast results of wrinkle removals and faces slimming.

Made Collagen is an Italian brand used to make mesotherapy. It will be injected with a special technique to stimulate collagen production at 16 points to add moisture to the skin to get a bright face. Moreover, it can reduce acne and allergies while add nutrients, and detox the skin.
Made Collagen activating through 4 steps
1. Detoxification
2. Metabolism
3. Nutrients and Cell therapy
4. Restructuring

Ultraformer is about lifting the face, tightening the skin, adjusting the shape of the face, and dissolving fat. You will see results in the first time. It hurts a little but can restore youthfulness to the skin. Using high frequency sound waves Highly concentrated, it releases energy specifically to the desired depth location. Without this surgery or surgery It's called Hifu (blue check mark) machine technology. Brand Ultraformer III is the best Hifu machine, equivalent to ULTHERA because it is a Macrofocus system that has been certified to European standards. Macrofocus

Can last up to 6 months - 1 year, depending on the care of the person receiving the service.

Diode Laser technology is recommended for hair removal with permanent results, while IPL is recommended for hair reduction. This is because lasers create more heat and light energy directly concentrated to the hair follicle and only target melanin (the pigment that gives hair its colour), while the light energy of IPL diffuses on the skin surrounding the hair follicle.

Treatment takes approximately 15-30 minutes, depending on the area

Filler Belotero is featured in high flexibility and contains an anesthetic. The filler can last for 18 months. It can solve problems in areas with deep folds caused by the aging process or the increasing age such as nasolabial folds and sunken cheeks

Cytocare is a skin injection product characterized by a clear solution. Nucleic acids Antioxidants, vitamins, minerals, and more than 50 types of minerals that make up rejuvenating complex CT50 contain a variety of substances that feed the skin and antioxidants, which contribute to reducing wrinkles. Restores skin to look more moisturized and radiant.

xeo.min (botulinum To.xin, Germany) is a development of Allergan and Dysport, emphasizing purity.According to research, it is a brand that doesn't case the drug resistant. Doctors will use it on patients who have been resistant to the drug before, but must be spaced 3-4 years before injecting into patients

Diode Laser technology is recommended for hair removal with permanent results, while IPL is recommended for hair reduction. This is because lasers create more heat and light energy directly concentrated to the hair follicle and only target melanin (the pigment that gives hair its colour), while the light energy of IPL diffuses on the skin surrounding the hair follicle.

Treatment takes approximately 15-30 minutes, depending on the area

Facial treatment is the process of caring for, treating or nourishing the face in different ways. Depending on the purpose of the procedure, such as facial tightening treatments, there may be exfoliation of new skin cells. All three methods that work together are treatments to tighten the face.

Juvederm filler is a filler imported from America. With hylacross technology, Juvederm has high flexibility due to the gel texture. It is featured in the smoothness, which is suitable for people with wrinkle problems, caused by age-related changes, and who want to adjust the face shape. It is commonly used to fill cheeks or marionette lines

xeo.min (botulinum To.xin, Germany) is a development of Allergan and Dysport, emphasizing purity.According to research, it is a brand that doesn't case the drug resistant. Doctors will use it on patients who have been resistant to the drug before, but must be spaced 3-4 years before injecting into patients